---
title: "[2610.00010] Meta-Analysis of the Expansion in the Field of Structural Biology of ABC Transporters"
description: "ABC transporters are molecular machines which power the solute transport using ATP hydrolysis. The structural biology of ABC transporters has been exploding…"
url: "https://cccurj.org/abs/2610.00010"
license: "CC BY 4.0"
---

Quantitative Biology > Biomolecules

[Submitted on 19 Oct 2026]

**Republished example · not submitted to CCCURJ.** This work, written by or with California Community College students, first appeared in BioDesign Research 2022:9806979 (2022) on September 8, 2022 under CC BY 4.0. It is shown here unchanged, with the openly licensed PDF, as an example of the research CCC students do; its authors did not submit it and CCCURJ editors did not review it. Read and cite [the original](https://doi.org/10.34133/2022/9806979).

# Meta-Analysis of the Expansion in the Field of Structural Biology of ABC Transporters

[Soomi Kim](https://cccurj.org/search#Soomi_Kim), [Teena Bajaj](https://cccurj.org/search#Teena_Bajaj), [Cole Chabon](https://cccurj.org/search#Cole_Chabon), [Eric Tablante](https://cccurj.org/search#Eric_Tablante), [Tatyana Kulchinskaya](https://cccurj.org/search#Tatyana_Kulchinskaya), [Tae Seok Moon](https://cccurj.org/search#Tae_Seok_Moon), [Ruchika Bajaj](https://cccurj.org/search#Ruchika_Bajaj)

> ABC transporters are molecular machines which power the solute transport using ATP hydrolysis. The structural biology of ABC transporters has been exploding for the last few years, and this study explores timelines and trends for various attributes such as structural tools, resolution, fold, sources, and group leaders. This study also evidences the significance of mammalian expression systems, advancements in structural biology tools, and the developing interest of group leaders across the world in the remarkably progressing field. The field started in 2002 and bloomed in 2016, and COVID years were really productive to the field. Specifically, the study explores 337 structures of 58 unique ABC transporters deposited in the PDB database from which P-glycoprotein has the largest number of structures. Approximately, 62% of total structures are determined at the resolution of 3-4 Å and 53% of structures belong to fold IV type. With progressive advancements in the field, the field is shifting from prokaryotic to eukaryotic sources and X-ray crystallography to cryoelectron microscopy. In the nutshell, this study uniquely provides the detailed snapshot of the field of structural biology of ABC transporters with real-time data.

- Artifact type: [Literature review](https://cccurj.org/help/artifacts#literature-review)
- Comments: 12 pages. Republished from BioDesign Research 2022:9806979 (2022) under CC BY 4.0; not submitted to CCCURJ
- Subjects: Biomolecules (q-bio.BM)
- Journal reference: BioDesign Research 2022:9806979 (2022)
- Cite as: the original, <https://doi.org/10.34133/2022/9806979>
- Related DOI: <https://doi.org/10.34133/2022/9806979>

## Submission history

From: CCCURJ editors (republished)
**[v1]** Mon, 19 Oct 2026 17:00:00 UTC (766 KB)

[Report a concern about this paper or its authors](https://cccurj.org/account/report/paper/2610.00010) (plagiarism, fabricated results, misconduct)

### Bibliographic and Citation Tools

**BibTeX citation**

```
@misc{kim2022expansion,
      title={Meta-Analysis of the Expansion in the Field of Structural Biology of ABC Transporters},
      author={Soomi Kim and Teena Bajaj and Cole Chabon and Eric Tablante and Tatyana Kulchinskaya and Tae Seok Moon and Ruchika Bajaj},
      year={2022},
      howpublished={BioDesign Research 2022:9806979 (2022)},
      doi={10.34133/2022/9806979},
      url={https://doi.org/10.34133/2022/9806979},
}
```

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